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KMID : 0381219920240010059
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Journal of RIMSK
1992 Volume.24 No. 1 p.59 ~ p.67
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A Clinical Study of Respiratory Syncytial Virus Infection in Infancy
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Abstract
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Respiratory syncytial virus(PSV) is the main cause of bronchiolitis and pneumonia in infancy. We performed clinical studies on 130 infants younger than 24 months of age with respiratory disease, who had been admitted to the department of
pediatrics,
Chung Ang University Hospital, from Aug 1990 to July 1991. The nasopharyngeal washing solution of patients were examined for detection of PSV antigen by ELISA and then we compared RSV antigen positive group with RSV antigen negative group on
aspects of
clinical manifestation, radiologic finding, including serum IgE level.
@ES The results were as follows:
@EN 1) A total of 24 patients(18 boys and 6 girls) was in RSV antigen positive while 106 patients (65 body and 41 girls) were RSV antigen negative. Male to female ratio was 3 : 1 in RSV antigen positive group and 1.5 : 1 in RSV antigen negative
group.
2) The subjected patients were diagnosed to have acute bronchiolitis is in 58 cases, 57 pneumonia, 6 nasonpharyngitis, 6 laryngitis and 3 bronchitis. Of 58 bronchiolitis patients, 14(24.1%) were antigen positive whereas 9 of 57 pneumonia(15.8%)
and 1
of 5 laryngitis(16.6%) were RSV antigen positive.
3) During the observed period from August 1990 to July 1991, RSV infection was sporadically occurred rather than epidemic.
4) mean hospital days in RSV antigen positive group(6.8±1.8 days) was significantly shorter than those in RSV antigen negative group(8.0±5.3)(p value<0.05).
5) No significant difference was noted in clinical manifestations and radiologic findings between those in RSV antigen positive group and negative group.
6) Mean serum Ige level was higher in RSV antigen negative group(26.9±31.5IU/ml) than RSV antigen positive group(8.8±11.6), but there was no statistically significance(p value>0.05)
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